Yes, we have lived in one off and on since 2008. We have decided that it is the only way to go and have bought a new rig that is for full timers. I will never own another house, rent an apartment, etc. The ability to see the country, meet different people is really indescribable. I lived in houses and apartments and most people never know their neighbors. Go to a RV park and you will meet a lot of people. Most are very friendly, there are a few that aren't, but I can hook up and leave.
As far as problems with the units, some is maintenance related, some is manufacture problems. Add up all the people that have RV's and those with major problems, IMHO the percentage will be small. Sure many will have small problems here and there, but these unit suffer the equivalent of a CONSTANT earthquake while we go down the road. Subject your house to 16 hours of a earthquake and see what is left, so a RV does do pretty well.
In short, it is all what you want and expect from a RV.
On a side note; My 3 mo old $65k truck has had more problems than my RV has.