If you use a gooseneck hitch, you also need a pin box that will manage the gooseneck without putting excess stress on the trailer frame. Reese Goosebox for example.
Also, the payload spec on an F-250 is probably way too low for a Cyclone. Assume 20% of the trailer GVWR will be on the hitch. Add to that the weight of the hitch, bed liner, bed cover, tools, firewood, pets, passengers and anything else in the truck. Compare that number to the actual payload spec of the exact truck under consideration.