I run with a set of 19.5" Rickson Wheels. I put on Toyo M143Z 245/70R 19.5 and M608Z 245/70R 19.5. The size of the tires matches the height of the OEM. Didn't find any 19.5" wheels that could handle 110 PSI - had to go to steel. This was a couple of years ago - may have changed.
The ride is a little stiffer (but with the trailer it is not that noticeable). With the tires being stiffer, the wind and cornering is less squishy than with the OEM tires. The tires stand very tall now like my trailer tires. I do swap out my system back to my OEM tires/wheels since I need 4 wheel drive for snow. My OEM tires were showing heavy weight wear after 25k miles and I rotated them every 5k miles.
I put a Dill Air Control TPMS on both the truck and trailer and now have real time TPMS monitoring (Running 110 PSI causes an error message with the OEM TPMS). I also put Air Lift air bags on so that bumps put less stress on the suspension (I noticed that with the helper bar for my 1 ton, there was contact with the springs and jouncer).