Hi Fireliter,
We take our Landmark to Breckenridge, Colorado for extended ski trips (6 weeks last winter) and have had many nights of subzero temps. No skirting.
Having a dual pane windows, a fireplace and a ceramic disc heater (we have a Pelonis) helps. Staying warm is not a problem.
Keeping water systems from freezing takes more.
You'll have to keep the furnace thermostat turned up so the underbelly stays warm. That's the first line of defense for your water lines. Hopefully you have tank heating pads or Yeti Option, otherwise your water tanks may freeze. I'm not sure how cold it gets in Lexington, but you don't want to risk your tanks.
We keep a 60w drop lamp running in the UDC to keep the water connections from freezing. For sub-freezing weather, you'll either need a heated water hose or put heat tape and insulation on a regular hose. Another alternative is to fill the fresh water tank during the day and disconnect the hose.
Keeping a 100W heat lamp running behind the basement wall (over the water pump and plumbing connections) will be important as temps drop toward zero. Just make sure it's mounted well so it can't fall onto the floor.
If you install a pvc sewer pipe, and put heat tape and insulation on it, you can leave your gray valves open without fear of creating an ice dam.
If you have an icemaker and/or water in the frig door, you'll have to shut off that water feed line in the basement and evacuate water from the line and frig. That water line won't survive a freeze.
If you'll be there all winter, skirting may be appropriate.
If you can rent a large propane tank, that will save the aggravation of frequently filling the tanks.
If you have slide awnings, you'll need to support them and plan on clearing the snow off them to prevent damage.
We've done it - you can too.