Mark - Laser's are like coffee or tea.
I have the S&W Bodyguard which comes with a Laser, works good. But I find in the daytime or good lighting I can easily shoot better groups quicker with the sights. The little 380 is very good "point and shoot", easy to control pocket pistol.
In the bedroom - middle of the night , I think the laser would be the preferred choice.
Either way, you of course have to practice with the never fail iron sights and if you go for a Laser, stick with name brands and expect to pay similar prices. All in one light laser etc on eBay for 30 bucks will be worthless when you really need it.
That said, I only have one weapon laser, but he next item I am looking at is the S&W Gov with the factory installed Crimson Trace laser. That will be the RV piece.
The PX Fury - still waiting for the pricing to come down, but that would probably cause more short term pain then a 9mm!