Quoted from Wikepedia:
"An inline six engine is in perfect primary and secondary mechanical balance, which can be achieved without using a balance shaft. The engine is in primary balance because the front and rear trio of cylinders are mirror images, and the
pistons move in pairs. That is, piston #1 balances #6, #2 balances #5, and #3 balances #4, largely eliminating the polar rocking motion that would otherwise result. Secondary imbalance is avoided because an inline six cylinder crankshaft has six crank throws arranged in three planes offset at 120 degrees. The result is that differences in piston speed at any given point in rotation are effectively canceled."
I agree that the V8 is a very smooth engine, but the inline 6 achieves it without all the complexity.