Regardless of all the hype, the one thing which I will atest to is that from my experience Nitrogen filled tires tend to stay at 80 psi without dropping for month after month. "Regular" air always seems to weep out just a little over time, thus necessitating air-ups on a regular basis. Not a problem if you check your air pressure regularly but who does that.
All snake oil as far as normal automotive and recreational use is concerned.
Pressure dropping over time? I'd say it is more a tire issue then whether you have 78% N or 92-95% N
I bought my GoodYear G-114's in August 2010, so this past spring is the 4th time I did a spring get ready and still had the same pressure I parked the trailer with 4-5 months prior.
If the trailer is parked with 115 in November, they usually have 115 in the spring.
Pulling a vacuum? Can't do it. But, proper N installation does involve evacuating the tire to some negative pressure.
Real N filling? Most of the real world experts agree that best case scenario is a final N content of 92-95%
Just doesn't make sense to us to go through the extra trouble.
Now, if you are running a NASCAR Ford or Chevy at 200+ with huge tires and and a relatively low pressure where the difference of 1/2 a PSI can mean the difference of doing the burnout at the end or going straight to the trailer - N does have it's place.
I would guess there are very few folks that actually have a pressure gauge that is accurate enough to really benefit from the whole N controversy.